Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_003103: Rickettsia conorii str. Malish 7, complete genome

NCBI: NC_003103

Host Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
112114*3207519962Island text2.977813.144526.205Neighbours21BLASTN+12114.gbk
270000*9245822459Island text2.7400111.58221.9089Neighbours21BLASTN+70000.gbk
3164972*18767122700Island text1.5083313.205225.6943Neighbours21BLASTN+164972.gbk
422595624833922384Island text1.6995212.706724.93Neighbours21BLASTN+225956.gbk
5266013*28459918587Island text1.4159113.691614.746Neighbours21BLASTN266013.gbk
6563961*58206318103Island text1.4901114.269224.5462Neighbours21BLASTN563961.gbk
7919000*93693317934Island text2.2676312.889125.2345Neighbours21BLASTN919000.gbk
81133806115644922644Island text1.4856919.497832.44Neighbours21BLASTN1133806.gbk