Pre_GI Gene

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Host: NC_017518 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017518:795113 Neisseria meningitidis NZ-05/33 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
7951137963871275tetrahydrofolate synthasedihydrofolate synthaseQuickGO ontologyBLASTP
796419796859441putative transcriptional regulator FolIQuickGO ontologyBLASTP
796864797223360hypothetical proteinBLASTP
797296798024729polar amino acid ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
798197798976780dimethyladenosine transferaseQuickGO ontologyBLASTP
799173799862690hypothetical proteinBLASTP
8000478012491203tryptophan synthase subunit betaQuickGO ontologyBLASTP
8091728114542283DNA internalization-related competence protein ComECRec2QuickGO ontologyBLASTP
811512812315804competence lipoprotein comLQuickGO ontologyBLASTP
8123148134381125ribosomal large subunit pseudouridine synthase DQuickGO ontologyBLASTP
813591814538948transporter bile acidNa symporter familyQuickGO ontologyBLASTP
815097815876780hypothetical proteinBLASTP
815928816407480rare lipoprotein B familyQuickGO ontologyBLASTP
816409817407999DNA polymerase III subunit deltaQuickGO ontologyBLASTP
817528817947420hypothetical proteinBLASTP
817971818537567RDD family proteinQuickGO ontologyBLASTP