Pre_GI Gene

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Host: NC_017518 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017518:672790 Neisseria meningitidis NZ-05/33 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
6727906738241035copper ABC transporter periplasmic copper-binding proteinQuickGO ontologyBLASTP
674641675135495nosL proteinQuickGO ontologyBLASTP
6752236768841662electron-transferring-flavoprotein dehydrogenaseQuickGO ontologyBLASTP
677014677556543peptidase C39 familyQuickGO ontologyBLASTP
678076679041966transposase IS30 familyQuickGO ontologyBLASTP
679712680098387C2 transposaseQuickGO ontologyBLASTP
680077680334258ABC transporter protein-1 exporterQuickGO ontologyBLASTP
683756684295540hypothetical proteinBLASTP
684466685119654hypothetical proteinBLASTP
686232686885654hypothetical proteinBLASTP
690211691125915ABC transporter substrate-binding proteinQuickGO ontologyBLASTP
691202692077876ABC transporter permeaseQuickGO ontologyBLASTP
692112692867756ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
69315969352436650S ribosomal protein L19QuickGO ontologyBLASTP
693540694289750tRNA guanine-N1-methyltransferaseQuickGO ontologyBLASTP
69428969479851016S rRNA processing protein RimMQuickGO ontologyBLASTP
69481469505924630S ribosomal protein S16QuickGO ontologyBLASTP
6951046975302427CoA binding domainacetyltransferase GNAT familyQuickGO ontologyBLASTP
6976486990541407putative sensor histidine kinase CpxAQuickGO ontologyBLASTP
699068699745678putative transcriptional regulatory protein CpxRQuickGO ontologyBLASTP