Pre_GI Gene

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Host: NC_017518 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017518:577159 Neisseria meningitidis NZ-05/33 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
5771595786521494ribonuclease GQuickGO ontologyBLASTP
578866579123258glutaredoxin 3QuickGO ontologyBLASTP
579144579587444protein-export chaperone SecBQuickGO ontologyBLASTP
5796735817152043ATP-dependent DNA helicase RecGQuickGO ontologyBLASTP
5827795838221044N-acetyl-gamma-glutamyl-phosphate reductaseQuickGO ontologyBLASTP
583819584100282hypothetical proteinBLASTP
5844685856221155cupin family proteinQuickGO ontologyBLASTP
587553587855303hypothetical proteinBLASTP
587873588040168hypothetical proteinBLASTP
588249588371123hypothetical proteinBLASTP
5884395901811743hemolysin secretionactivation protein ShlB familyQuickGO ontologyBLASTP
5902905962685979hemagglutininhemolysin-like proteinQuickGO ontologyBLASTP
596287596661375hypothetical proteinBLASTP
5970715995212451hemagglutininhemolysin family proteinQuickGO ontologyBLASTP
599518600006489hypothetical proteinBLASTP