Pre_GI Gene

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Host: NC_017518 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017518:1701958 Neisseria meningitidis NZ-05/33 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
17019581702395438ribonuclease HIQuickGO ontologyBLASTP
17037461704150405histidine triad family proteinQuickGO ontologyBLASTP
170419017053741185muramoyltetrapeptide carboxypeptidaseQuickGO ontologyBLASTP
17054371705970534glutathione peroxidaseQuickGO ontologyBLASTP
170614917084042256nitric oxide reductaseQuickGO ontologyBLASTP
170880217099771176copper-containing nitrite reductaseQuickGO ontologyBLASTP
17101571710912756hypothetical proteinBLASTP
171249417137081215replication initiation factorQuickGO ontologyBLASTP
17137201714031312hypothetical proteinBLASTP
17140351714235201hypothetical proteinBLASTP
17144731714703231hypothetical proteinBLASTP
17147311715033303hypothetical proteinBLASTP
171538017169931614tspB proteinQuickGO ontologyBLASTP
171758217186851104zonula occludens toxin family proteinQuickGO ontologyBLASTP
17189841719940957transposase IS116IS110IS902 familyQuickGO ontologyBLASTP
17213161722014699opacity proteinQuickGO ontologyBLASTP
17222151722772558nitroreductase family proteinQuickGO ontologyBLASTP
172284817244821635putative sulfataseQuickGO ontologyBLASTP