Pre_GI Gene

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Host: NC_017518 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017518:1610803 Neisseria meningitidis NZ-05/33 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
161080316125751773DNA primaseQuickGO ontologyBLASTP
161276116146891929RNA polymerase sigma factor rpoDQuickGO ontologyBLASTP
161710816183221215replication initiation factorQuickGO ontologyBLASTP
16183341618645312hypothetical proteinBLASTP
16186491618849201hypothetical proteinBLASTP
16190871619317231hypothetical proteinBLASTP
16193451619647303hypothetical proteinBLASTP
161999416216071614tspB proteinQuickGO ontologyBLASTP
162219616232991104zonula occludens toxin family proteinQuickGO ontologyBLASTP
16235981624554957transposase IS116IS110IS902 familyQuickGO ontologyBLASTP
162554316283772835lactoferrin-binding protein AQuickGO ontologyBLASTP
162837416305212148lactoferrin-binding protein BQuickGO ontologyBLASTP