Pre_GI Gene

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Host: NC_017518 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017518:1558000 Neisseria meningitidis NZ-05/33 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
155804415608092766heme-utilization protein HupQuickGO ontologyBLASTP
15620401562996957transposase IS116IS110IS902 familyQuickGO ontologyBLASTP
156329515643981104zonula occludens toxin family proteinQuickGO ontologyBLASTP
156498715666001614tspB proteinQuickGO ontologyBLASTP
15669471567249303hypothetical proteinBLASTP
15672771567507231hypothetical proteinBLASTP
15677451567945201hypothetical proteinBLASTP
15679491568260312hypothetical proteinBLASTP
156827215695401269replication initiation factorQuickGO ontologyBLASTP
157148915727061218aspartate kinaseQuickGO ontologyBLASTP
15729081573636729ribonuclease PHQuickGO ontologyBLASTP
15737181574182465universal stress protein familyQuickGO ontologyBLASTP
15743991575175777thiF family proteinQuickGO ontologyBLASTP
15754201576274855segregation and condensation protein BQuickGO ontologyBLASTP
157631515775231209nicotinate phosphoribosyltransferaseQuickGO ontologyBLASTP
157761515793331719arginyl-tRNA synthetaseQuickGO ontologyBLASTP