Pre_GI Gene

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Host: NC_017518 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017518:1449923 Neisseria meningitidis NZ-05/33 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
144992314505616392-dehydro-3-deoxyphosphogluconate aldolaseQuickGO ontologyBLASTP
145202114530611041AG-specific adenine glycosylaseQuickGO ontologyBLASTP
14534781454038561hypothetical proteinBLASTP
14543771455198822hypothetical proteinBLASTP
145585414579862133type I secretion system ATPaseQuickGO ontologyBLASTP
14587371459243507hypothetical proteinBLASTP
145926014602671008hypothetical proteinBLASTP
14615981462137540hypothetical proteinBLASTP
14623081462961654transposaseQuickGO ontologyBLASTP
14635681464383816FrpC operon proteinQuickGO ontologyBLASTP
146804114706442604membrane alanyl aminopeptidaseQuickGO ontologyBLASTP
14708561471650795hypothetical proteinBLASTP
14717671471925159hypothetical proteinBLASTP
14724011473282882lipid A biosynthesis KDO2-lauroyl-lipid IVA acyltransferaseQuickGO ontologyBLASTP
14733211473857537crossover junction endodeoxyribonuclease RuvCQuickGO ontologyBLASTP
14738601474099240Fis family transcriptional regulatorQuickGO ontologyBLASTP
147413014751401011dihydrouridine synthaseQuickGO ontologyBLASTP