Pre_GI Gene

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Host: NC_017517 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017517:867595 Neisseria meningitidis M01-240355 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
8675958687461152hypothetical proteinBLASTP
8688508701481299adenylosuccinate synthetaseQuickGO ontologyBLASTP
870385871224840peptidase M48 familyQuickGO ontologyBLASTP
871439872086648adenylate kinaseQuickGO ontologyBLASTP
872612873352741orotidine 5-phosphate decarboxylaseQuickGO ontologyBLASTP
873408874379972hldE bifunctional protein domain IQuickGO ontologyBLASTP
8744168756511236DNA-cytosine methyltransferaseQuickGO ontologyBLASTP
8756538766841032hypothetical proteinBLASTP
8768138778171005ADP-glyceromanno-heptose 6-epimeraseQuickGO ontologyBLASTP
8778948794351542type I restriction-modification system M subunitQuickGO ontologyBLASTP
8847358870232289ATP-dependent Clp protease ATP-binding subunit ClpAQuickGO ontologyBLASTP
887025887327303ATP-dependent Clp protease adaptor protein ClpSQuickGO ontologyBLASTP
887531887773243putative transcriptional regulatorQuickGO ontologyBLASTP
8880708894011332protein PmbAQuickGO ontologyBLASTP
889554890060507hypothetical proteinBLASTP