Pre_GI Gene

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Host: NC_017517 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017517:749031 Neisseria meningitidis M01-240355 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
7490317503051275tetrahydrofolate synthasedihydrofolate synthaseQuickGO ontologyBLASTP
750336750782447putative transcriptional regulator FolIQuickGO ontologyBLASTP
750787751146360hypothetical proteinBLASTP
751219751947729polar amino acid ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
752120752899780dimethyladenosine transferaseQuickGO ontologyBLASTP
753111753800690hypothetical proteinBLASTP
7538837550851203tryptophan synthase subunit betaQuickGO ontologyBLASTP
7552647605975334IgA-specific serine endopeptidaseQuickGO ontologyBLASTP
7624707634771008transposase IS4 familyQuickGO ontologyBLASTP
7641167661912076DNA internalization-related competence protein ComECRec2QuickGO ontologyBLASTP
766249767052804competence lipoprotein comLQuickGO ontologyBLASTP
7670517681751125ribosomal large subunit pseudouridine synthase DQuickGO ontologyBLASTP
768328769275948transporter bile acidNa symporter familyQuickGO ontologyBLASTP
769834770613780hypothetical proteinBLASTP
770665771144480rare lipoprotein B familyQuickGO ontologyBLASTP
771146772144999DNA polymerase III subunit deltaQuickGO ontologyBLASTP