Pre_GI Gene

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Host: NC_017517 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017517:635235 Neisseria meningitidis M01-240355 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
636102636596495nosL proteinQuickGO ontologyBLASTP
6366846383451662electron-transferring-flavoprotein dehydrogenaseQuickGO ontologyBLASTP
639891640856966transposase IS30 familyQuickGO ontologyBLASTP
641641642180540putative transposaseQuickGO ontologyBLASTP
642787643596810FrpC operon proteinQuickGO ontologyBLASTP
643786644115330putative transposaseQuickGO ontologyBLASTP
644369645184816FrpC operon proteinQuickGO ontologyBLASTP
6452016485093309Iron-regulated protein frpCQuickGO ontologyBLASTP
648789649703915ABC transporter substrate-binding proteinQuickGO ontologyBLASTP
649780650655876ABC transporter permeaseQuickGO ontologyBLASTP
650679651434756ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
65172665209136650S ribosomal protein L19QuickGO ontologyBLASTP
652107652856750tRNA guanine-N1-methyltransferaseQuickGO ontologyBLASTP
65285665333848316S rRNA processing protein RimMQuickGO ontologyBLASTP
65338165362624630S ribosomal protein S16QuickGO ontologyBLASTP
6536716560972427CoA binding domainacetyltransferase GNAT familyQuickGO ontologyBLASTP
6562156576211407putative sensor histidine kinase CpxAQuickGO ontologyBLASTP