Pre_GI Gene

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Host: NC_017517 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017517:1409000 Neisseria meningitidis M01-240355 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
141043014114701041AG-specific adenine glycosylaseQuickGO ontologyBLASTP
14118871412447561superoxide dismutase Cu-ZnQuickGO ontologyBLASTP
14127851413501717hypothetical proteinBLASTP
141416914163972229type I secretion system ATPaseQuickGO ontologyBLASTP
14165791416716138hypothetical proteinBLASTP
14172101417749540putative transposaseQuickGO ontologyBLASTP
14180751418509435hypothetical proteinBLASTP
14188511419504654hypothetical proteinBLASTP
14197221420720999RTX prokaryotic toxin family proteinQuickGO ontologyBLASTP
14223591422643285iron-regulated protein frpAQuickGO ontologyBLASTP
14231811423738558iron-regulated protein frpAQuickGO ontologyBLASTP
14243821424513132hypothetical proteinBLASTP
142520314282353033Iron-regulated protein frpCQuickGO ontologyBLASTP