Pre_GI Gene

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Host: NC_017517 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017517:1377617 Neisseria meningitidis M01-240355 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
13776171378171555putative lipoproteinQuickGO ontologyBLASTP
13782561378756501hypothetical proteinBLASTP
137916013803561197acetylornithine transaminasesuccinyldiaminopimelate transaminaseQuickGO ontologyBLASTP
138045913817031245ATP-dependent Clp protease ATP-binding subunit ClpXQuickGO ontologyBLASTP
13818931382264372ribosome-binding factor AQuickGO ontologyBLASTP
13822751382799525hypothetical proteinBLASTP
13828571383777921tRNA pseudouridine synthase BQuickGO ontologyBLASTP
138627813890492772type III restriction enzyme res subunitQuickGO ontologyBLASTP
138919813903581161L-lactate dehydrogenaseQuickGO ontologyBLASTP
13907201391166447iron-sulfur cluster assembly transcription factor IscRQuickGO ontologyBLASTP
139119513924091215cysteine desulfurase IscSQuickGO ontologyBLASTP
13930201393139120hypothetical protein
13932071393593387FeS cluster assembly scaffold IscUQuickGO ontologyBLASTP
13936801394000321iron-sulfur cluster assembly protein IscAQuickGO ontologyBLASTP
13939601394181222hypothetical proteinBLASTP
13942631394763501Fe-S protein assembly co-chaperone HscBQuickGO ontologyBLASTP
139486113976112751DNA gyrase subunit AQuickGO ontologyBLASTP
13992151399766552hypothetical proteinBLASTP
139978014014261647glucose-6-phosphate isomeraseQuickGO ontologyBLASTP