Pre_GI Gene

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Host: NC_017516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017516:96879 Neisseria meningitidis H44/76 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
96879980931215sodiumglutamate symporterQuickGO ontologyBLASTP
98192992081017putative lipoproteinQuickGO ontologyBLASTP
9921999416198hypothetical proteinBLASTP
998411012411401outer membrane protein OMPP1FadLTodX familyQuickGO ontologyBLASTP
1015561030281473pyruvate kinaseQuickGO ontologyBLASTP
103460103789330putative transposaseQuickGO ontologyBLASTP
109695109841147hypothetical proteinBLASTP
110086110421336putative transposaseQuickGO ontologyBLASTP
110646111197552hypothetical proteinBLASTP
112470113027558hypothetical proteinBLASTP
113271113429159putative lipoproteinQuickGO ontologyBLASTP
113426114268843GNAT family acetyltransferaseQuickGO ontologyBLASTP
114507115427921aspartate carbamoyltransferaseQuickGO ontologyBLASTP
115437115895459aspartate carbamoyltransferase regulatory subunitQuickGO ontologyBLASTP
115960116625666hypothetical proteinBLASTP
1166881179051218LysM domain-containing proteinQuickGO ontologyBLASTP
118089118592504peptide deformylaseQuickGO ontologyBLASTP
118679119605927methionyl-tRNA formyltransferaseQuickGO ontologyBLASTP
1196841209431260ribosomal RNA small subunit methyltransferase BQuickGO ontologyBLASTP
120909121505597hypothetical proteinBLASTP
1215051236252121sensor histidine kinaseQuickGO ontologyBLASTP
1236181248951278DNA-binding response regulator Fis familyQuickGO ontologyBLASTP