Pre_GI Gene

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Host: NC_017516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017516:917817 Neisseria meningitidis H44/76 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
917817918272456hypothetical proteinBLASTP
9188919216412751DNA gyrase subunit AQuickGO ontologyBLASTP
921739922239501Fe-S protein assembly co-chaperone HscBQuickGO ontologyBLASTP
922321922542222hypothetical proteinBLASTP
922502922822321iron-sulfur cluster assembly protein IscAQuickGO ontologyBLASTP
922909923295387FeS cluster assembly scaffold IscUQuickGO ontologyBLASTP
923365923574210hypothetical proteinBLASTP
9235599247731215cysteine desulfurase IscSQuickGO ontologyBLASTP
924802925248447iron-sulfur cluster assembly transcription factor IscRQuickGO ontologyBLASTP
9255519267111161L-lactate dehydrogenaseQuickGO ontologyBLASTP
931945932868924tRNA pseudouridine synthase BQuickGO ontologyBLASTP
932901933272372ribosome-binding factor AQuickGO ontologyBLASTP
9334639347071245ATP-dependent Clp protease ATP-binding subunit ClpXQuickGO ontologyBLASTP
9348109360061197acetylornithine transaminasesuccinyldiaminopimelate transaminaseQuickGO ontologyBLASTP
936410936910501hypothetical proteinBLASTP
936995937549555putative lipoproteinQuickGO ontologyBLASTP
9380389394261389putative ATP-dependent RNA helicase rhlEQuickGO ontologyBLASTP
939754940701948hypothetical proteinBLASTP