Pre_GI Gene

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Host: NC_017516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017516:879834 Neisseria meningitidis H44/76 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
879834880628795hypothetical proteinBLASTP
8807598833622604membrane alanyl aminopeptidaseQuickGO ontologyBLASTP
8837048879934290Iron-regulated protein frpCQuickGO ontologyBLASTP
888010888783774FrpC operon proteinQuickGO ontologyBLASTP
889556890365810FrpC operon proteinQuickGO ontologyBLASTP
890972891625654putative transposaseQuickGO ontologyBLASTP
891796891927132hypothetical proteinBLASTP
892572892892321iron-regulated protein frpAQuickGO ontologyBLASTP
893698893970273iron-regulated protein frpAQuickGO ontologyBLASTP
895609896607999RTX prokaryotic toxin family proteinQuickGO ontologyBLASTP
896825897478654hypothetical proteinBLASTP
897820898254435hypothetical proteinBLASTP
898591899130540putative transposaseQuickGO ontologyBLASTP
899624899761138hypothetical proteinBLASTP
8999439021712229type I secretion system ATPaseQuickGO ontologyBLASTP
902428903402975transposase IS4 familyQuickGO ontologyBLASTP
903967904527561hypothetical proteinBLASTP
9049449059931050AG-specific adenine glycosylaseQuickGO ontologyBLASTP
9061479071871041zinc-containing alcohol dehydrogenaseQuickGO ontologyBLASTP
9074469080846392-dehydro-3-deoxyphosphogluconate aldolaseQuickGO ontologyBLASTP
9082659101001836phosphogluconate dehydrataseQuickGO ontologyBLASTP
910563910733171hypothetical protein
911251912114864glucose-6-phosphate dehydrogenaseQuickGO ontologyBLASTP