Pre_GI Gene

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Host: NC_017516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017516:364404 Neisseria meningitidis H44/76 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
364404365213810shikimate 5-dehydrogenaseQuickGO ontologyBLASTP
3655133669311419glutamine synthetase type IQuickGO ontologyBLASTP
3671353683701236permease AmpG familyQuickGO ontologyBLASTP
368367368642276GIY-YIG catalytic domain-containing proteinQuickGO ontologyBLASTP
369631370404774FrpC operon proteinQuickGO ontologyBLASTP
3707833719161134hypothetical proteinBLASTP
371980372357378hypothetical proteinBLASTP
372435372893459hypothetical proteinBLASTP
372874373263390hypothetical proteinBLASTP
373395373772378hypothetical proteinBLASTP
373850374308459hypothetical proteinBLASTP
374289374678390hypothetical proteinBLASTP
374810375187378hypothetical proteinBLASTP
375209375616408hypothetical proteinBLASTP
375622376299678hypothetical proteinBLASTP
376514376873360hypothetical proteinBLASTP
3768763782791404hypothetical proteinBLASTP
378283379224942putative lipoprotein MafA familyQuickGO ontologyBLASTP
3793443804441101anhydro-N-acetylmuramic acid kinaseQuickGO ontologyBLASTP
3807653823391575phosphate transporter family proteinQuickGO ontologyBLASTP
3826923841131422oxygen-independent coproporphyrinogen III oxidaseQuickGO ontologyBLASTP
384318385052735CarD family transcriptional regulatorQuickGO ontologyBLASTP
385165386115951putative transcriptional regulator CysBQuickGO ontologyBLASTP