Pre_GI Gene

Some Help

Host: NC_017516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017516:123618 Neisseria meningitidis H44/76 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1215051236252121sensor histidine kinaseQuickGO ontologyBLASTP
1236181248951278DNA-binding response regulator Fis familyQuickGO ontologyBLASTP
1249861261791194putative DNA processing protein DprAQuickGO ontologyBLASTP
126205126666462hypothetical proteinBLASTP
1267381290442307DNA topoisomerase IQuickGO ontologyBLASTP
129117129812696hypothetical proteinBLASTP
129832130383552hypothetical proteinBLASTP
130562130879318DNA-binding proteinQuickGO ontologyBLASTP
130968131537570methyltransferase family proteinQuickGO ontologyBLASTP
131660131911252iron-sulfur cluster-binding proteinQuickGO ontologyBLASTP
13200813209184tRNA-TyrQuickGO ontologyBLASTP
1323281335121185translation elongation factor TuQuickGO ontologyBLASTP
13351913359476tRNA-TrpQuickGO ontologyBLASTP
133709133987279Preprotein translocase subunit SecEQuickGO ontologyBLASTP
133989134525537transcription terminationantitermination factor NusGQuickGO ontologyBLASTP
13462613506043550S ribosomal protein L11QuickGO ontologyBLASTP
13506013575569650S ribosomal protein L1QuickGO ontologyBLASTP
13598513648550150S ribosomal protein L10QuickGO ontologyBLASTP
13654313691437250S ribosomal protein L7L12QuickGO ontologyBLASTP
1371041412824179DNA-directed RNA polymerase subunit betaQuickGO ontologyBLASTP
1414391456144176DNA-directed RNA polymerase subunit betaQuickGO ontologyBLASTP
145906146163258hypothetical proteinBLASTP
146160146309150hypothetical proteinBLASTP