Pre_GI Gene

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Host: NC_017515 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017515:875500 Neisseria meningitidis M04-240196 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
875693875851159hypothetical proteinBLASTP
875965876759795hypothetical proteinBLASTP
8768908794932604membrane alanyl aminopeptidaseQuickGO ontologyBLASTP
8798268837733948iron-regulated protein FrpAQuickGO ontologyBLASTP
884563885561999RTX prokaryotic toxin family proteinQuickGO ontologyBLASTP
885779886432654hypothetical proteinBLASTP
886774887208435hypothetical proteinBLASTP
887545888084540putative transposaseQuickGO ontologyBLASTP
888578888715138hypothetical proteinBLASTP
8889938911252133type I secretion system ATPaseQuickGO ontologyBLASTP
892943893503561superoxide dismutase Cu-ZnQuickGO ontologyBLASTP
8939208949601041AG-specific adenine glycosylaseQuickGO ontologyBLASTP
8964218970596392-dehydro-3-deoxyphosphogluconate aldolaseQuickGO ontologyBLASTP
8972408990751836phosphogluconate dehydrataseQuickGO ontologyBLASTP