Pre_GI Gene

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Host: NC_017515 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017515:76861 Neisseria meningitidis M04-240196 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
7686177205345BLASTP
78231805042274S1 RNA binding domain-containing proteinQuickGO ontologyBLASTP
8056881218651capsule polysaccharide export ATP-binding protein CtrDQuickGO ontologyBLASTP
8121582012798capsule polysaccharide export inner-membrane protein CtrCQuickGO ontologyBLASTP
82012831751164capsule polysaccharide export inner-membrane protein CtrBQuickGO ontologyBLASTP
83190843651176capsule polysaccharide export outer membrane protein CtrAQuickGO ontologyBLASTP
8474185280540transposase IS4 familyQuickGO ontologyBLASTP
85337864701134UDP-N-acetylglucosamine 2-epimeraseQuickGO ontologyBLASTP
8647487160687N-acylneuraminate cytidylyltransferaseQuickGO ontologyBLASTP
87161882101050polysialic acid capsule biosynthesis protein SiaCQuickGO ontologyBLASTP
88294897811488alpha-28-polysialyltransferase SiaDQuickGO ontologyBLASTP
9027791230954hypothetical proteinBLASTP
91613926321020UDP-glucose 4-epimeraseQuickGO ontologyBLASTP
92748938151068dTDP-glucose 46-dehydrataseQuickGO ontologyBLASTP
9387894744867glucose-1-phosphate thymidylyltransferaseQuickGO ontologyBLASTP
9486595830966transposase IS30 familyQuickGO ontologyBLASTP
9584096448609transposase IS4 familyQuickGO ontologyBLASTP
9679597334540dTDP-4-dehydrorhamnose 35-epimeraseQuickGO ontologyBLASTP
97358994722115capsule polysaccharide modification protein LipAQuickGO ontologyBLASTP
996091008681260capsule polysaccharide modification protein LipBQuickGO ontologyBLASTP
1012351026411407sel1tetratricopeptide repeat proteinQuickGO ontologyBLASTP
1028591040731215sodiumglutamate symporterQuickGO ontologyBLASTP
1041721051881017putative lipoproteinQuickGO ontologyBLASTP
105199105396198hypothetical proteinBLASTP
1058211072211401outer membrane protein OMPP1FadLTodX familyQuickGO ontologyBLASTP
1075291090011473pyruvate kinaseQuickGO ontologyBLASTP
109433109762330putative transposaseQuickGO ontologyBLASTP
115669115815147hypothetical proteinBLASTP
115895116395501putative transposaseQuickGO ontologyBLASTP
116620117171552hypothetical proteinBLASTP
118444119001558hypothetical proteinBLASTP
119245119403159putative lipoproteinQuickGO ontologyBLASTP
119400120242843GNAT family acetyltransferaseQuickGO ontologyBLASTP
120481121401921aspartate carbamoyltransferaseQuickGO ontologyBLASTP
121411121869459aspartate carbamoyltransferase regulatory subunitQuickGO ontologyBLASTP
121934122599666BLASTP
1226621238791218LysM domain-containing proteinQuickGO ontologyBLASTP
124063124566504peptide deformylaseQuickGO ontologyBLASTP
124653125579927methionyl-tRNA formyltransferaseQuickGO ontologyBLASTP
1256581269171260ribosomal RNA small subunit methyltransferase BQuickGO ontologyBLASTP
126883127482600hypothetical proteinBLASTP
1274821296022121sensor histidine kinaseQuickGO ontologyBLASTP
1295951308721278DNA-binding response regulator Fis familyQuickGO ontologyBLASTP