Pre_GI Gene

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Host: NC_017515 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017515:372487 Neisseria meningitidis M04-240196 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
3724873739051419glutamine synthetase type IQuickGO ontologyBLASTP
3740563753391284permease AmpG familyQuickGO ontologyBLASTP
375336375611276GIY-YIG catalytic domain-containing proteinQuickGO ontologyBLASTP
375998376771774FrpC operon proteinQuickGO ontologyBLASTP
3771503782831134hypothetical proteinBLASTP
378458378838381hypothetical proteinBLASTP
378922379299378hypothetical proteinBLASTP
379368379853486hypothetical proteinBLASTP
379804380433630hypothetical proteinBLASTP
380582380812231hypothetical proteinBLASTP
382615382842228hypothetical proteinBLASTP
382901383224324hypothetical proteinBLASTP
383214383567354hypothetical proteinBLASTP
383864384412549hypothetical proteinBLASTP
3844023862191818MafB family proteinQuickGO ontologyBLASTP
386223387164942putative lipoprotein MafA familyQuickGO ontologyBLASTP
3872833883831101anhydro-N-acetylmuramic acid kinaseQuickGO ontologyBLASTP
3906333920541422oxygen-independent coproporphyrinogen III oxidaseQuickGO ontologyBLASTP
392257392991735CarD family transcriptional regulatorQuickGO ontologyBLASTP