Pre_GI Gene

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Host: NC_017515 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017515:1555500 Neisseria meningitidis M04-240196 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
15555401556487948transporter bile acidNa symporter familyQuickGO ontologyBLASTP
155663915577631125ribosomal large subunit pseudouridine synthase DQuickGO ontologyBLASTP
15577621558565804competence lipoprotein comLQuickGO ontologyBLASTP
155862315609052283DNA internalization-related competence protein ComECRec2QuickGO ontologyBLASTP
156213415674945361IgA-specific serine endopeptidaseQuickGO ontologyBLASTP
156767315688751203tryptophan synthase subunit betaQuickGO ontologyBLASTP
15690601569770711hypothetical proteinBLASTP
15699821570761780dimethyladenosine transferaseQuickGO ontologyBLASTP
15709341571662729polar amino acid ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
15717351572094360hypothetical proteinBLASTP
15720991572545447putative transcriptional regulator FolIQuickGO ontologyBLASTP
157257715738511275tetrahydrofolate synthasedihydrofolate synthaseQuickGO ontologyBLASTP