Pre_GI Gene

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Host: NC_017515 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017515:1429317 Neisseria meningitidis M04-240196 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
142931714306481332protein PmbAQuickGO ontologyBLASTP
14309451431187243putative transcriptional regulatorQuickGO ontologyBLASTP
14313911431693303ATP-dependent Clp protease adaptor protein ClpSQuickGO ontologyBLASTP
143169514339862292ATP-dependent Clp protease ATP-binding subunit ClpAQuickGO ontologyBLASTP
143402514371233099HsdR family type I site-specific deoxyribonucleaseQuickGO ontologyBLASTP
143916714407081542type I restriction-modification system M subunitQuickGO ontologyBLASTP
144078514417891005ADP-glyceromanno-heptose 6-epimeraseQuickGO ontologyBLASTP
144295114441861236DNA-cytosine methyltransferaseQuickGO ontologyBLASTP
14442231445194972hldE bifunctional protein domain IQuickGO ontologyBLASTP
14452491445989741orotidine 5-phosphate decarboxylaseQuickGO ontologyBLASTP
14465151447162648adenylate kinaseQuickGO ontologyBLASTP
14473781448217840peptidase M48 familyQuickGO ontologyBLASTP
14485181449078561hypothetical proteinBLASTP
14491921449584393NUMOD1 domain proteinQuickGO ontologyBLASTP
14497921450196405hypothetical proteinBLASTP
14503011450711411hypothetical proteinBLASTP
14507251451162438hypothetical proteinBLASTP
14511341451454321hypothetical proteinBLASTP
145157314528711299adenylosuccinate synthetaseQuickGO ontologyBLASTP