Pre_GI Gene

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Host: NC_017514 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017514:96911 Neisseria meningitidis M01-240149 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
96911983921482hypothetical proteinBLASTP
987041000981395outer membrane protein OMPP1FadLTodX familyQuickGO ontologyBLASTP
1004111018831473pyruvate kinaseQuickGO ontologyBLASTP
1053271065921266MceHQuickGO ontologyBLASTP
1065951086822088toxin secretion ABC transporter permeaseATP-binding proteinQuickGO ontologyBLASTP
108907109053147hypothetical proteinBLASTP
1100951112491155GTP-binding protein ObgCgtAQuickGO ontologyBLASTP
1113321123811050hypothetical proteinBLASTP
1130691144901422cysteinyl-tRNA synthetaseQuickGO ontologyBLASTP
114661115440780exodeoxyribonuclease IIIQuickGO ontologyBLASTP
115427115771345hypothetical protein
115782116312531hypothetical protein
1165411176561116aspartate-semialdehyde dehydrogenaseQuickGO ontologyBLASTP
117985118566582RDD family proteinQuickGO ontology
118628119386759methylenetetrahydrofolate dehydrogenasemethenyltetrahydrofolate cyclohydrolaseQuickGO ontologyBLASTP
11991111998676tRNA-HisQuickGO ontology
120122120628507hldE bifunctional protein domain IIQuickGO ontologyBLASTP
1206251224031779biotin-acetyl-CoA-carboxylase ligasetranscriptional activator Baf familyQuickGO ontologyBLASTP