Pre_GI Gene

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Host: NC_017514 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017514:863485 Neisseria meningitidis M01-240149 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
863485863643159hypothetical proteinBLASTP
863760864554795hypothetical proteinBLASTP
8647668673692604membrane alanyl aminopeptidaseQuickGO ontologyBLASTP
8677118710193309Iron-regulated protein frpCQuickGO ontologyBLASTP
871036871770735FrpC operon proteinQuickGO ontologyBLASTP
872458873111654putative transposaseQuickGO ontologyBLASTP
873282873821540hypothetical proteinBLASTP
874142874615474iron-regulated protein frpAQuickGO ontologyBLASTP
8751528761591008iron-regulated protein frpAQuickGO ontologyBLASTP
8773378795652229type I secretion system ATPaseQuickGO ontologyBLASTP
880221881042822hypothetical proteinBLASTP
881381881941561hypothetical proteinBLASTP
8823588833981041AG-specific adenine glycosylaseQuickGO ontologyBLASTP
8848588854966392-dehydro-3-deoxyphosphogluconate aldolaseQuickGO ontologyBLASTP
8856778875121836phosphogluconate dehydrataseQuickGO ontologyBLASTP
8880288894731446glucose-6-phosphate dehydrogenaseQuickGO ontologyBLASTP