Pre_GI Gene

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Host: NC_017514 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017514:761000 Neisseria meningitidis M01-240149 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
761050761514465universal stress protein familyQuickGO ontologyBLASTP
761596762324729ribonuclease PHQuickGO ontologyBLASTP
7625267637431218aspartate kinaseQuickGO ontologyBLASTP
766235766960726Replication initiation factor family proteinQuickGO ontologyBLASTP
766972767283312hypothetical proteinBLASTP
767287767487201hypothetical proteinBLASTP
767725767955231hypothetical proteinBLASTP
767983768285303hypothetical proteinBLASTP
7689507702451296Neisseria meningitidis TspB family proteinQuickGO ontologyBLASTP
770549770833285hypothetical proteinBLASTP
7708497719371089hypothetical proteinBLASTP
772236773192957putative transposaseQuickGO ontologyBLASTP
7744237771372715heme-utilization protein HupQuickGO ontologyBLASTP
778961779155195hypothetical proteinBLASTP
7791457812262082carbon starvation protein AQuickGO ontologyBLASTP