Pre_GI Gene

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Host: NC_017514 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017514:1885154 Neisseria meningitidis M01-240149 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
188515418867281575phosphate transporter family proteinQuickGO ontologyBLASTP
188705018881531104anhydro-N-acetylmuramic acid kinaseQuickGO ontologyBLASTP
18882721889213942putative lipoprotein MafA familyQuickGO ontologyBLASTP
18902731890971699hypothetical proteinBLASTP
18909551891308354hypothetical proteinBLASTP
18912981891621324hypothetical proteinBLASTP
18918561892125270hypothetical proteinBLASTP
18922461892791546hypothetical proteinBLASTP
18929251893554630hypothetical proteinBLASTP
18935351893990456hypothetical proteinBLASTP
18940681894445378hypothetical proteinBLASTP
18948281895151324hypothetical proteinBLASTP
18952511895811561hypothetical proteinBLASTP
189593118970641134hypothetical proteinBLASTP
18974431898153711FrpC operon proteinQuickGO ontologyBLASTP
18986151898890276GIY-YIG catalytic domain-containing proteinQuickGO ontologyBLASTP
189888719001701284permease AmpG familyQuickGO ontologyBLASTP
190032119017391419glutamine synthetase type IQuickGO ontologyBLASTP
19020431902852810shikimate 5-dehydrogenaseQuickGO ontologyBLASTP
19028541903555702monofunctional biosynthetic peptidoglycan transglycosylaseQuickGO ontologyBLASTP