Pre_GI Gene

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Host: NC_017514 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017514:1520245 Neisseria meningitidis M01-240149 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
15202451521192948transporter bile acidNa symporter familyQuickGO ontologyBLASTP
152134515224691125ribosomal large subunit pseudouridine synthase DQuickGO ontologyBLASTP
15224681523271804competence lipoprotein comLQuickGO ontologyBLASTP
152332915254042076DNA internalization-related competence protein ComECRec2QuickGO ontologyBLASTP
152796815334185451IgA-specific serine endopeptidaseQuickGO ontologyBLASTP
153359615347981203tryptophan synthase subunit betaQuickGO ontologyBLASTP
15349831535672690hypothetical proteinBLASTP
15358691536648780dimethyladenosine transferaseQuickGO ontologyBLASTP
15368211537549729polar amino acid ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
15376221537981360hypothetical proteinBLASTP
15379861538426441putative transcriptional regulator FolIQuickGO ontologyBLASTP
153845815397321275tetrahydrofolate synthasedihydrofolate synthaseQuickGO ontologyBLASTP
15397451540743999cell division protein FtsNQuickGO ontologyBLASTP
15407361541233498cvpA family proteinQuickGO ontologyBLASTP