Pre_GI Gene

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Host: NC_017514 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017514:1491235 Neisseria meningitidis M01-240149 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
14912351491711477chorismate--pyruvate lyaseQuickGO ontologyBLASTP
14917261492373648dethiobiotin synthaseQuickGO ontologyBLASTP
149237014936711302adenosylmethionine-8-amino-7-oxononanoate transaminaseQuickGO ontologyBLASTP
14938851494124240hypothetical proteinBLASTP
14943841494869486cytoplasmic membrane protein fxsAQuickGO ontologyBLASTP
14951991495489291hypothetical proteinBLASTP
14954911495793303integration host factor subunit alphaQuickGO ontologyBLASTP
149586714982302364phenylalanyl-tRNA synthetase subunit betaQuickGO ontologyBLASTP
14982551498905651putative DNA methylaseQuickGO ontologyBLASTP
149890215003711470type II restriction enzymeQuickGO ontologyBLASTP
150037415014291056DNA-cytosine methyltransferaseQuickGO ontologyBLASTP
15016151502607993phenylalanyl-tRNA synthetase subunit alphaQuickGO ontologyBLASTP
15026841502893210hypothetical proteinBLASTP
1502953150331236050S ribosomal protein L20QuickGO ontologyBLASTP
1503325150361829450S ribosomal protein L35QuickGO ontologyBLASTP
15036691504073405translation initiation factor IF-3QuickGO ontologyBLASTP
150420815061211914threonyl-tRNA synthetaseQuickGO ontologyBLASTP
150643015075451116queuine tRNA-ribosyltransferaseQuickGO ontologyBLASTP
150762715086371011ferrochelataseQuickGO ontologyBLASTP
15088291509230402cytochrome c family proteinQuickGO ontologyBLASTP