Pre_GI Gene

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Host: NC_017514 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017514:1396000 Neisseria meningitidis M01-240149 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
13960431396285243putative transcriptional regulatorQuickGO ontologyBLASTP
13964891396791303ATP-dependent Clp protease adaptor protein ClpSQuickGO ontologyBLASTP
139679313990842292ATP-dependent Clp protease ATP-binding subunit ClpAQuickGO ontologyBLASTP
139912414022553132HsdR family type I site-specific deoxyribonucleaseQuickGO ontologyBLASTP
140428814058291542type I restriction-modification system M subunitQuickGO ontologyBLASTP
140590514069091005ADP-glyceromanno-heptose 6-epimeraseQuickGO ontologyBLASTP
140695014080681119type II restriction enzymeQuickGO ontologyBLASTP
140807014093051236DNA-cytosine methyltransferaseQuickGO ontologyBLASTP
14093421410313972hldE bifunctional protein domain IQuickGO ontologyBLASTP
14103681411108741orotidine 5-phosphate decarboxylaseQuickGO ontologyBLASTP
14116341412281648adenylate kinaseQuickGO ontologyBLASTP
14124961413335840peptidase M48 familyQuickGO ontologyBLASTP
14136381414342705hypothetical proteinBLASTP
14143111414703393NUMOD1 domain proteinQuickGO ontologyBLASTP
14149111415315405hypothetical proteinBLASTP
14154201415830411hypothetical proteinBLASTP
14158441416281438hypothetical proteinBLASTP
14162531416573321hypothetical proteinBLASTP
141669214179901299adenylosuccinate synthetaseQuickGO ontologyBLASTP
141809414192451152hypothetical proteinBLASTP