Pre_GI Gene

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Host: NC_017513 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017513:887344 Neisseria meningitidis G2136 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
887344887817474Peptidase M15 family proteinQuickGO ontologyBLASTP
887814888338525hypothetical proteinBLASTP
888391888738348putative plasmid toxin protein PemKQuickGO ontologyBLASTP
888740888976237putative plasmid toxin protein PemIQuickGO ontologyBLASTP
889335889826492hypothetical proteinBLASTP
890264890632369death-on-curing family proteinQuickGO ontologyBLASTP
890629890760132hypothetical proteinBLASTP
8911768921831008hypothetical proteinBLASTP
892224893063840hypothetical proteinBLASTP
893086893229144hypothetical proteinBLASTP
8933338945951263auxiliary transport protein membrane fusion protein MFP familyQuickGO ontologyBLASTP
8945978966092013peptidase C39 familyQuickGO ontologyBLASTP
897087897293207hypothetical proteinBLASTP
8973008984631164cupin family proteinQuickGO ontologyBLASTP
898525899064540transposase IS4 familyQuickGO ontologyBLASTP
899484899687204hypothetical proteinBLASTP
9007219017281008transposase IS4 familyQuickGO ontologyBLASTP
9028929051172226isocitrate dehydrogenaseQuickGO ontologyBLASTP
905186905347162hypothetical proteinBLASTP
9055509066651116CMP-N-acetylneuraminate-beta-galactosamide-alpha -23-sialyltransferaseQuickGO ontologyBLASTP
906830907288459cytochrome c class IIQuickGO ontologyBLASTP
907407908228822NADP-dependent L-serineL-allo-threonine dehydrogenase ydfGQuickGO ontologyBLASTP
908279908725447thioesterase family proteinQuickGO ontologyBLASTP
909932910624693opacity proteinQuickGO ontologyBLASTP
911427912392966transposase IS30 familyQuickGO ontologyBLASTP