Pre_GI Gene

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Host: NC_017513 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017513:449949 Neisseria meningitidis G2136 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
449949450392444protein-export chaperone SecBQuickGO ontologyBLASTP
4504784525202043ATP-dependent DNA helicase RecGQuickGO ontologyBLASTP
4537764548191044N-acetyl-gamma-glutamyl-phosphate reductaseQuickGO ontologyBLASTP
454816455097282hypothetical proteinBLASTP
458356458658303hypothetical proteinBLASTP
458676458843168hypothetical proteinBLASTP
459052459165114hypothetical proteinBLASTP
4595694609841416hemolysin secretionactivation protein ShlB familyQuickGO ontologyBLASTP
4610944671746081hemagglutininhemolysin family proteinQuickGO ontologyBLASTP
467181467690510hypothetical proteinBLASTP
4677594698402082hemagglutininhemolysin family proteinQuickGO ontologyBLASTP
469859470233375hypothetical proteinBLASTP
4705464720481503hypothetical proteinBLASTP
472175472330156hypothetical proteinBLASTP
4724374748242388hypothetical proteinBLASTP
474829475212384hypothetical proteinBLASTP
475196475324129hypothetical protein
4758584781462289hypothetical proteinBLASTP
478162478593432hypothetical proteinBLASTP
478741479706966transposase IS30 familyQuickGO ontologyBLASTP