Pre_GI Gene

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Host: NC_017513 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017513:2017000 Neisseria meningitidis G2136 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
201701320209753963phosphoribosylformylglycinamidine synthaseQuickGO ontologyBLASTP
20210702021828759hydroxyacylglutathione hydrolaseQuickGO ontologyBLASTP
202684920283031455magnesium transporterQuickGO ontologyBLASTP
20283892029297909chaperonin HslOQuickGO ontologyBLASTP
20295422030297756nlpCp60 family proteinQuickGO ontologyBLASTP
20303162030534219hypothetical proteinBLASTP
20306792031023345LrgA family proteinQuickGO ontologyBLASTP
20310232031715693LrgB family proteinQuickGO ontologyBLASTP
203178220330021221glutamate N-acetyltransferaseamino-acid acetyltransferaseQuickGO ontologyBLASTP
203306220344711410chloride transporter ClC familyQuickGO ontologyBLASTP