Pre_GI Gene

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Host: NC_017513 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017513:1331623 Neisseria meningitidis G2136 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
133162313322616392-dehydro-3-deoxyphosphogluconate aldolaseQuickGO ontologyBLASTP
133372313347631041AG-specific adenine glycosylaseQuickGO ontologyBLASTP
13351801335740561superoxide dismutase Cu-ZnQuickGO ontologyBLASTP
13363261336826501hypothetical proteinBLASTP
133749413397222229type I secretion system ATPaseQuickGO ontologyBLASTP
13399041340041138hypothetical proteinBLASTP
13404221341075654putative transposaseQuickGO ontologyBLASTP
13414121341846435hypothetical proteinBLASTP
13421881342841654hypothetical proteinBLASTP
13430591344057999RTX prokaryotic toxin family proteinQuickGO ontologyBLASTP
13465181347075558iron-regulated protein frpAQuickGO ontologyBLASTP
13477191347850132hypothetical proteinBLASTP
134854013533994860Iron-regulated protein frpCQuickGO ontologyBLASTP
135371513563182604membrane alanyl aminopeptidaseQuickGO ontologyBLASTP
13565301357324795hypothetical proteinBLASTP
13574411357626186hypothetical proteinBLASTP
13580741358943870lipid A biosynthesis KDO2-lauroyl-lipid IVA acyltransferaseQuickGO ontologyBLASTP
13589941359530537crossover junction endodeoxyribonuclease RuvCQuickGO ontologyBLASTP
13595331359772240Fis family transcriptional regulatorQuickGO ontologyBLASTP
135980213608121011dihydrouridine synthaseQuickGO ontologyBLASTP