Pre_GI Gene

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Host: NC_017512 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017512:760000 Neisseria meningitidis WUE 2594, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
760110760502393hypothetical proteinBLASTP
760563760790228hypothetical proteinBLASTP
760708761268561hypothetical proteinBLASTP
761571762410840putative HtpX-like proteaseQuickGO ontologyBLASTP
762625763272648adenylate kinase and related kinaseQuickGO ontologyBLASTP
763798764538741orotidine 5-phosphate decarboxylase OMP decarboxylase OMPDCase OMPdecaseQuickGO ontologyBLASTP
764593765564972D-beta-D-heptose 7-phosphate kinase D-beta-D-heptose 7-phosphotransferaseQuickGO ontologyBLASTP
7656017668361236putative type II restriction-modification system enzyme ModQuickGO ontologyBLASTP
7668387679561119putative type II restriction-modification system enzyme ResQuickGO ontologyBLASTP
7679977690011005ADP-L-glycero-D-manno-heptose-6-epimeraseQuickGO ontologyBLASTP
7690747706181545putative type I restriction-modification system M proteinQuickGO ontologyBLASTP
7706157716251011hypothetical proteinBLASTP
7762337785122280ATP-dependent Clp protease ATP-binding subunit ClpAQuickGO ontologyBLASTP
778514778816303ATP-dependent Clp protease adapter protein clpSQuickGO ontologyBLASTP
779059779262204putative cold shock proteinQuickGO ontologyBLASTP
7795607808911332putative PmbA-like proteinQuickGO ontologyBLASTP
780982781557576hypothetical proteinBLASTP
781604782317714hypothetical proteinBLASTP