Pre_GI Gene

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Host: NC_017512 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017512:642229 Neisseria meningitidis WUE 2594, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
642229643008780dimethyladenosine transferase S-adenosylmethionine-6-N N-adenosylrRNA dimethyltransferase 16S rRNA dimethylase high level kasugamycin resistanQuickGO ontologyBLASTP
643205643894690putative DNA glycosylaseQuickGO ontologyBLASTP
6440796452811203tryptophan synthase beta chainQuickGO ontologyBLASTP
6454606508955436IgA-specific serine endopeptidase IgA proteaseQuickGO ontologyBLASTP
6522936545752283Competence protein comAQuickGO ontologyBLASTP
654633655436804competence lipoprotein ComLQuickGO ontologyBLASTP
6553816565591179ribosomal large subunit pseudouridine synthase DQuickGO ontologyBLASTP
656712657704993Solute carrier family 10 member 6 Sodium-dependent organic anion transporterQuickGO ontologyBLASTP
658220658999780hypothetical proteinBLASTP
659051659530480hypothetical proteinBLASTP
659532660530999DNA polymerase III subunit deltaQuickGO ontologyBLASTP