Pre_GI Gene

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Host: NC_017512 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017512:526892 Neisseria meningitidis WUE 2594, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
5268925286491758putative electron transfer flavoprotein-ubiquinone oxidoreductase ETF-QO ETF-ubiquinone oxidoreductase ETF dehydrogenase electron-transferring-flaQuickGO ontologyBLASTP
528683529138456hypothetical proteinBLASTP
530099530890792IS1655 transposase pseudogene part 1QuickGO ontologyBLASTP
531597532250654IS1016 group transposaseQuickGO ontologyBLASTP
532936533901966putative pilin gene-inverting protein PIVMLQuickGO ontologyBLASTP
5347625358201059putative zonular occludens toxin-like proteinQuickGO ontologyBLASTP
535823536110288hypothetical proteinBLASTP
5361125376381527putative TspB proteinQuickGO ontologyBLASTP
537568537873306hypothetical proteinBLASTP
538002538277276hypothetical proteinBLASTP
538288538506219hypothetical proteinBLASTP
538589538792204hypothetical proteinBLASTP
538810539121312hypothetical proteinBLASTP
5391425404911350putative phage replication initiation factorQuickGO ontologyBLASTP
540488540703216hypothetical proteinBLASTP
540989541510522hypothetical proteinBLASTP
541560542009450hypothetical proteinBLASTP
542043542549507hypothetical proteinBLASTP