Pre_GI Gene

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Host: NC_017512 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017512:425085 Neisseria meningitidis WUE 2594, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
4250854265781494ribonuclease GQuickGO ontologyBLASTP
426792427049258glutaredoxinQuickGO ontologyBLASTP
427070427513444preprotein translocase SecB subunitQuickGO ontologyBLASTP
4275994296412043ATP-dependent DNA helicase RecGQuickGO ontologyBLASTP
4306214316641044N-acetyl-gamma-glutamyl-phosphate reductase AGPR N-acetyl-glutamate semialdehyde dehydrogenase NAGSA dehydrogenaseQuickGO ontologyBLASTP
431661431954294hypothetical proteinBLASTP
432322432642321hypothetical proteinBLASTP
433479433706228hypothetical proteinBLASTP
433699434052354hypothetical proteinBLASTP
436015436185171hypothetical proteinBLASTP
436284436523240hypothetical proteinBLASTP
4365844383261743TpsA activationsecretion protein TpsBQuickGO ontologyBLASTP
4384364444836048hemagglutininhemolysin-related protein TpsAQuickGO ontologyBLASTP
444488444871384hypothetical proteinBLASTP
447818448249432hypothetical proteinBLASTP
457029457517489hypothetical proteinBLASTP