Pre_GI Gene

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Host: NC_017512 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017512:2209000 Neisseria meningitidis WUE 2594, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
22093172209766450hypothetical proteinBLASTP
22098402210148309hypothetical protein
22102642211106843hypothetical proteinBLASTP
22110572211842786hypothetical proteinBLASTP
22118642212451588putative ECF-family RNA polymerase sigma factorQuickGO ontologyBLASTP
22124572212636180hypothetical proteinBLASTP
22128952213317423hypothetical proteinBLASTP
22154922216094603putative RNA-binding proteinQuickGO ontologyBLASTP
221612822173991272phosphoribosylamine-glycine ligase GARS glycinamide ribonucleotide synthetase phosphoribosylglycinamide synthetaseQuickGO ontologyBLASTP
22175562217873318hypothetical proteinBLASTP
22179252218536612hypothetical proteinBLASTP
22185992219534936electron transfer flavoprotein alpha-subunit alpha-ETF electron transfer flavoprotein large subunit ETFLSQuickGO ontologyBLASTP
22195452220294750electron transfer flavoprotein beta-subunit beta-ETF electron transfer flavoprotein small subunit ETFSSQuickGO ontologyBLASTP
22205202221488969lipooligosaccharide alpha-15 heptosyltransferase IQuickGO ontologyBLASTP
22215252222160636putative nicotinamidase nicotine deamidase NAMaseQuickGO ontologyBLASTP
22222752222955681hypothetical proteinBLASTP
222321322242171005glyceraldehyde-3-phosphate dehydrogenase B GAPDHQuickGO ontologyBLASTP
222466122272552595DNA mismatch repair protein MutSQuickGO ontologyBLASTP