Pre_GI Gene

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Host: NC_017512 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017512:1294970 Neisseria meningitidis WUE 2594, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
129621612972561041AG-specific adenine glycosylaseQuickGO ontologyBLASTP
1297343129743896hypothetical proteinBLASTP
12976731298233561superoxide dismutase Cu-ZnQuickGO ontologyBLASTP
12998541300819966IS1655 transposaseQuickGO ontologyBLASTP
13039331304472540IS1016 group transposaseQuickGO ontologyBLASTP
13048091305243435hypothetical proteinBLASTP
13052841305475192FrpAC-like proteinQuickGO ontologyBLASTP
13055101306238729hypothetical proteinBLASTP
130976713123702604aminopeptidase N alpha-aminoacylpeptide hydrolaseQuickGO ontologyBLASTP
13125011313295795putative polynucleotidyl transferaseQuickGO ontologyBLASTP
13140441314925882putative lipid A biosynthesis KDO2-lauroyl-lipid IVA acyltransferaseQuickGO ontologyBLASTP
13149641315500537crossover junction endodeoxyribonuclease RuvC Holliday junction nuclease RuvC Holliday junction resolvase RuvCQuickGO ontologyBLASTP
13155031315742240putative Fis-like DNA-binding proteinQuickGO ontologyBLASTP
13162381317203966IS1655 transposaseQuickGO ontologyBLASTP
131823113196041374putative ATP-dependent RNA helicaseQuickGO ontologyBLASTP