Pre_GI Gene

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Host: NC_017512 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017512:1264542 Neisseria meningitidis WUE 2594, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
12645421265042501hypothetical proteinBLASTP
126544612666391194acetylornithinesuccinyldiaminopimelate aminotransferase ACOAT succinyldiaminopimelate transferase DapATaseQuickGO ontologyBLASTP
126670412679481245ATP-dependent Clp protease ATP-binding subunit ClpXQuickGO ontologyBLASTP
12681391268510372ribosome-binding factor AQuickGO ontologyBLASTP
12685001269045546hypothetical proteinBLASTP
12691031270023921tRNA pseudouridine synthase B tRNA pseudouridine 55 synthase Psi55 synthase tRNA-uridine isomerase tRNA pseudouridylate synthaseQuickGO ontologyBLASTP
127247912752592781putative type III restriction-modification system enzyme ResQuickGO ontologyBLASTP
127540312765751173L-lactate dehydrogenase cytochromeQuickGO ontologyBLASTP
12768651277311447iron-sulfur cluster-assembly HTH-type transcriptional repressor IscRQuickGO ontologyBLASTP
127734012785541215cysteine desulfuraseQuickGO ontologyBLASTP
12786211278749129hypothetical proteinBLASTP
12788151279201387putative NifU-like proteinQuickGO ontologyBLASTP
12792881279608321putative IscA-like proteinQuickGO ontologyBLASTP
12795681279789222hypothetical proteinBLASTP
12798711280371501co-chaperone protein Hsc20QuickGO ontologyBLASTP
128046912832192751DNA gyrase subunit AQuickGO ontologyBLASTP