Pre_GI Gene

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Host: NC_017505 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017505:841496 Neisseria meningitidis alpha710 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
8414968426471152ATP phosphoribosyltransferase regulatory subunitQuickGO ontologyBLASTP
8427518440491299putative adenylosuccinate synthetaseQuickGO ontologyBLASTP
844434845273840heat shock protein HtpXQuickGO ontologyBLASTP
845488846135648adenylate kinaseQuickGO ontologyBLASTP
846661847401741putative orotidine 5-phosphate decarboxylaseQuickGO ontologyBLASTP
847456848427972putative DP-heptose synthetaseQuickGO ontologyBLASTP
8484648496991236C-5 cytosine-specific DNA methylaseQuickGO ontologyBLASTP
8508618518651005putative ADP-L-glycero-D-mannoheptose epimeraseQuickGO ontologyBLASTP
8519388534821545type I restriction enzyme EcoR124II M proteinQuickGO ontologyBLASTP
855219855404186hypothetical protein
8555268586573132putative type I restriction enzyme EcoR124II R proteinQuickGO ontologyBLASTP
8586978610062310putative ATP-dependent protease ATP-binding proteinQuickGO ontologyBLASTP
861008861310303putative ATP-dependent Clp protease adaptor protein clpSQuickGO ontologyBLASTP
861553861756204cold-shock domain-containing proteinQuickGO ontologyBLASTP
8620538633841332PmbA proteinQuickGO ontologyBLASTP
863533864045513hypothetical proteinBLASTP
864092864811720hypothetical proteinBLASTP