Pre_GI Gene

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Host: NC_017505 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017505:721395 Neisseria meningitidis alpha710 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
7213957226691275bifunctional folylpolyglutamate synthasedihydrofolate synthaseQuickGO ontologyBLASTP
722701723141441putative transcriptional regulatorQuickGO ontologyBLASTP
723146723505360hypothetical proteinBLASTP
723578724327750putative amino acid permease ATP-binding proteinQuickGO ontologyBLASTP
724479725258780putative dimethyladenosine transferaseQuickGO ontologyBLASTP
725455726144690hypothetical proteinBLASTP
7263297275311203putative tryptophan synthase beta chainQuickGO ontologyBLASTP
7277097331925484IgA1 proteaseQuickGO ontologyBLASTP
7354557377372283competence proteinQuickGO ontologyBLASTP
737795738598804competence lipoproteinQuickGO ontologyBLASTP
7385977397211125putative ribosomal large subunit pseudouridine synthase DQuickGO ontologyBLASTP
739873740865993putative transmembrane transport proteinQuickGO ontologyBLASTP
740897741088192hypothetical proteinBLASTP
741379742158780hypothetical proteinBLASTP
742210742689480putative lipoproteinQuickGO ontologyBLASTP
742691743689999putative DNA polymerase III delta subunitQuickGO ontologyBLASTP
743810744229420hypothetical proteinBLASTP