Pre_GI Gene

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Host: NC_017505 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017505:497603 Neisseria meningitidis alpha710 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
497603498250648hypothetical proteinBLASTP
498238499020783putative biotin synthesis protein BioCQuickGO ontologyBLASTP
4992405006761437hypothetical protein
5006795017761098hypothetical proteinBLASTP
501788502324537hypothetical proteinBLASTP
502326502970645hypothetical proteinBLASTP
502993503352360hypothetical proteinBLASTP
50344550352076tRNA-AsnQuickGO ontology
504019504471453putative cell-surface proteinQuickGO ontologyBLASTP
504398504730333hypothetical proteinBLASTP
504843505121279hypothetical proteinBLASTP
505128505412285hypothetical proteinBLASTP
505420505617198hypothetical proteinBLASTP
505622505912291hypothetical proteinBLASTP
5059575073121356putative phage replication initiation proteinQuickGO ontologyBLASTP
507508508473966IS1655 transposaseQuickGO ontologyBLASTP
5084625104351974hemagglutininhemolysin-related protein PspA- related proteinQuickGO ontologyBLASTP
5110285194698442putative hemagglutininQuickGO ontologyBLASTP
519597520082486putative replicative DNA helicaseQuickGO ontologyBLASTP
520179521162984replication proteinQuickGO ontologyBLASTP
5211095227881680putative hemolysin activatorQuickGO ontologyBLASTP
5228975270994203putative hemagglutininQuickGO ontologyBLASTP
527118527492375hypothetical proteinBLASTP
5278525303532502putative hemagglutininQuickGO ontologyBLASTP
530818531003186hypothetical protein
531688532293606hypothetical proteinBLASTP
5344715363361866putative hemagglutininQuickGO ontologyBLASTP