Pre_GI Gene

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Host: NC_017501 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017501:980848 Neisseria meningitidis 8013, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
980848981642795putative polynucleotidyl transferaseQuickGO ontologyBLASTP
9818549844572604aminopeptidase N alpha-aminoacylpeptide hydrolaseQuickGO ontologyBLASTP
9847999878373039FrpAC proteinQuickGO ontologyBLASTP
989141989869729hypothetical proteinBLASTP
989904990095192FrpAC-like proteinQuickGO ontologyBLASTP
990136990570435hypothetical proteinBLASTP
9922599944872229putative FrpAC translocation ATP-binding proteinQuickGO ontologyBLASTP
996135996695561superoxide dismutase Cu-ZnQuickGO ontologyBLASTP
996930997097168hypothetical proteinBLASTP
9971129981521041AG-specific adenine glycosylaseQuickGO ontologyBLASTP
9995161000154639KHGKDPG aldolase includes 4-hydroxy-2-oxoglutarate aldolase 2-keto-4-hydroxyglutarate aldolase KHG-aldolase and 2-dehydro-3-deoxy-phosphogluconaQuickGO ontologyBLASTP
100033510021701836phosphogluconate dehydrataseQuickGO ontologyBLASTP