Pre_GI Gene

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Host: NC_017501 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017501:1829500 Neisseria meningitidis 8013, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
18295921830014423putative 6-pyruvoyl tetrahydrobiopterin synthase PTPS PTP synthaseQuickGO ontologyBLASTP
18300211830539519hypothetical proteinBLASTP
18305671831226660hypothetical proteinBLASTP
1831229183127446PreQ1 riboswitchQuickGO ontology
183177118329971227tRNA-processing ribonuclease BNQuickGO ontologyBLASTP
18335111833969459hypothetical proteinBLASTP
18342521834530279hypothetical proteinBLASTP
18345331834736204hypothetical protein
18353011836236936hypothetical proteinBLASTP
18367471837181435hypothetical proteinBLASTP
18392351839609375hypothetical proteinBLASTP
18417781842287510hypothetical proteinBLASTP
184229418482215928hemagglutininhemolysin-related protein TpsA3QuickGO ontologyBLASTP
184833018500721743TpsA3 activationsecretion protein TpsB3QuickGO ontologyBLASTP