Pre_GI Gene

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Host: NC_017316 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017316:2710021 Enterococcus faecalis OG1RF chromosome, complete genome

Host Lineage: Enterococcus faecalis; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains. Enterococcus faecalis produces a cytolysin toxin that is encoded on various mobile genetic elements, pathogenicity islands, and conjugative plasmids. The cytolysin aids in pathogenesis, possibly by causing destruction of cells such as erythrocytes, which allows access to new nutrients for the organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
270900927100341026PTS family glucitolsorbitol porter IIB componentQuickGO ontologyBLASTP
27100212710575555PTS family glucitol glu porter component IICQuickGO ontologyBLASTP
27105752711060486transcriptional regulator SrlRQuickGO ontologyBLASTP
271105727129191863putative transcriptional activator SrlMQuickGO ontologyBLASTP
27129352713753819SDR family dehydrogenaseQuickGO ontologyBLASTP
271390727158051899tRNA uridine 5-carboxymethylaminomethyl modification protein GidAQuickGO ontologyBLASTP
271582527172221398tRNA modification GTPase TrmEQuickGO ontologyBLASTP
271745527224194965cell wall surface anchor family proteinQuickGO ontologyBLASTP
27226682722793126hypothetical protein
27231612724030870triphosphoribosyl-dephospho-CoA synthaseQuickGO ontologyBLASTP
272403727252691233malate dehydrogenase oxaloacetate-decarboxylating NADPQuickGO ontologyBLASTP
272532727267241398oxaloacetate decarboxylaseQuickGO ontologyBLASTP
272671727272535372-5-triphosphoribosyl-3-dephosphocoenzyme-A synthaseQuickGO ontologyBLASTP
272724627287781533citrate pro-3S-lyaseQuickGO ontologyBLASTP
27287812729668888citrate Pro-3S-lyaseQuickGO ontologyBLASTP
27296562729973318citrate lyase acyl carrier proteinQuickGO ontologyBLASTP
272997027309801011citrate pro-3S-lyase ligaseQuickGO ontologyBLASTP
27309952731129135hypothetical proteinBLASTP
273115127322661116glutaconyl-CoA decarboxylaseQuickGO ontologyBLASTP