Pre_GI Gene

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Host: NC_017316 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017316:2581781 Enterococcus faecalis OG1RF chromosome, complete genome

Host Lineage: Enterococcus faecalis; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains. Enterococcus faecalis produces a cytolysin toxin that is encoded on various mobile genetic elements, pathogenicity islands, and conjugative plasmids. The cytolysin aids in pathogenesis, possibly by causing destruction of cells such as erythrocytes, which allows access to new nutrients for the organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
25817812582665885hypothetical proteinBLASTP
25826902583187498RNA polymerase sigma-70 factorQuickGO ontologyBLASTP
258342425849051482M protein trans-acting positive regulatorQuickGO ontologyBLASTP
25848802585365486hypothetical proteinBLASTP
258547025865491080cell wall surface anchor family proteinQuickGO ontologyBLASTP
25866552587413759UbiD family decarboxylaseQuickGO ontologyBLASTP
25874142588214801WxL domain surface proteinQuickGO ontologyBLASTP
25882192588953735UbiD family decarboxylaseQuickGO ontologyBLASTP
25889842589217234hypothetical protein
258931925941754857WxL domain surface proteinQuickGO ontologyBLASTP
25943072594432126hypothetical protein
259454225955551014lipaseQuickGO ontologyBLASTP
25957212596266546isochorismatase transposaseQuickGO ontologyBLASTP
25964632597146684murein hydrolase regulator LrgBQuickGO ontologyBLASTP
25971432597562420murein hydrolase regulator LrgAQuickGO ontologyBLASTP
25977142598442729response regulatorQuickGO ontologyBLASTP
259842326001921770sensor histidine kinaseQuickGO ontologyBLASTP
26002842601102819ABC superfamily ATP binding cassette transporter binding proteinQuickGO ontologyBLASTP
26011152601786672metal ion ABC superfamily ATP binding cassette transporter membrane proteinQuickGO ontologyBLASTP
26017832602505723ABC superfamily ATP binding cassette transporter ABC proteinQuickGO ontologyBLASTP