Pre_GI Gene

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Host: NC_017270 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017270:885179 Vibrio cholerae LMA3984-4 chromosome chromosome I, complete

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
8883978894671071UDP-N-acetylglucosamine 2-epimeraseQuickGO ontologyBLASTP
8894878907281242UDP-N-acetyl-D-mannosaminuronate dehydrogenaseQuickGO ontologyBLASTP
890764891366603polysaccharide export protein putativeQuickGO ontologyBLASTP
8916938928471155CapK protein putativeQuickGO ontologyBLASTP
892850893821972hypothetical proteinBLASTP
893826894563738N-acetylmannosaminyltransferaseQuickGO ontologyBLASTP
894785895576792RbmA proteinQuickGO ontologyBLASTP
895781896620840hypothetical proteinBLASTP
8974889001482661Hemolysin-like protein RbmCQuickGO ontologyBLASTP
9003039016191317RbmD Lipid A core antigen ligaseQuickGO ontologyBLASTP
901793902080288hypothetical proteinBLASTP
9023429036101269Capsular polysaccharide synthesis enzyme CpsA sugar transferaseQuickGO ontologyBLASTP
9036819048771197Capsular polysaccharide synthesis enzyme CpsBQuickGO ontologyBLASTP
904881905408528Capsular polysaccharide synthesis enzyme CpsC polysaccharide exportQuickGO ontologyBLASTP
9054339076462214Capsular polysaccharide synthesis enzyme CpsD exopolysaccharide synthesisQuickGO ontologyBLASTP