Pre_GI Gene

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Host: NC_017270 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017270:220282 Vibrio cholerae LMA3984-4 chromosome chromosome I, complete

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
219905220285381capsular polysaccharide biosynthesis proteinQuickGO ontologyBLASTP
22028222156212813-deoxy-D-manno-octulosonic-acid transferaseQuickGO ontologyBLASTP
221562222344783Mannosyltransferase OCH1QuickGO ontologyBLASTP
2223472233961050lipopolysaccharide biosynthesis protein putativeQuickGO ontologyBLASTP
2233932244301038ADP-heptose--lipooligosaccharide heptosyltransferase putativeQuickGO ontologyBLASTP
2244302256291200O-antigen ligaseQuickGO ontologyBLASTP
225631226191561transferase hexapeptide repeat familyQuickGO ontologyBLASTP
2262052279771773polysaccharide deacetylaseQuickGO ontologyBLASTP
228136229080945ADP-L-glycero-D-manno-heptose-6-epimeraseQuickGO ontologyBLASTP
2296332309191287mannose-1-phosphate guanylyltransferaseQuickGO ontologyBLASTP
2309222323131392phosphomannomutaseQuickGO ontologyBLASTP
2323162334371122GDP-mannose 46-dehydrataseQuickGO ontologyBLASTP
2334482345511104Perosamine synthaseQuickGO ontologyBLASTP
2345572359391383O-antigen export system polymerase or transferaseQuickGO ontologyBLASTP
235932236705774O-antigen export system permease proteinQuickGO ontologyBLASTP
236707237459753O-antigen export system ATP-binding proteinQuickGO ontologyBLASTP
237507237740234acyl carrier proteinQuickGO ontologyBLASTP
2377462391611416long-chain-fatty-acid--CoA ligaseQuickGO ontologyBLASTP
2391702402941125Alcohol dehydrogenaseQuickGO ontologyBLASTP
2402852427622478Acyl protein synthaseacyl-CoA reductase RfbNQuickGO ontologyBLASTP
245474245659186hypothetical proteinBLASTP
245656246528873transposase OrfAB subunit BQuickGO ontologyBLASTP